Orbis Medicines is a pioneering biotech company dedicated to the future of drug discovery by leveraging cutting-edge chemistry and data-driven approaches to transform the treatment landscape. As a medicinal chemist at Orbis Medicines, you will be part of our newly established team in Copenhagen, Denmark, contributing to the discovery and development of innovative therapeutics.

Reporting directly to the VP of Medicinal Chemistry and Portfolio Management, you will have a key role in leading the design and synthesis of macrocycle projects, establish workflows, and drive crossfunctional collaborations. This position offers unparalleled opportunities for professional challenges as you tackle impactful projects in a rapidly evolving pipeline.

YOUR ROLE

• Design and develop in vitro / ex vivo assays to characterize the function and potency of potential drug candidates


• Plan and conduct assays in primary cells and cell lines and analyze cellular responses with a broad array of techniques


• Identify and implement new technologies, assay platforms and experimental methods in collaboration with colleagues


• Lead in vitro pharmacology efforts within projects to reach go/no-go decisions and contribute with understanding of disease mechanisms, cellular biology and guidance on overall translation


• Provide scientific input on project biomarker strategies, overseeing assay development and execution in collaboration with expert CRO’s

YOUR QUALIFICATIONS

• Ph.D. in biology, biomedicine, or a related field, with at least 5 years of industry experience in Pharma/Biotech, and a strong track record in drug discovery and early development


• Extensive hands-on expertise in mammalian cell culture, including primary immune cells and PBMCs


• Proven experience in assay development, troubleshooting, and optimization using various types of assay technologies (e.g. ligand-based assays, qPCR, and flow cytometry)


• Broad expertise in immunology and diseases driven by inflammatory processes


• A keen interest in lab-based work with a positive and solution-focused mindset


• A proactive and flexible team player, with strong collaboration skills, selfleadership, and the ability to manage multiple tasks of varying complexity


• Excellent communication skills, with the ability to present complex scientific data to diverse audiences.

CONTACT & APPLICATION

For further information about the position, please contact HR Partner Karin Zimmermann at +45 4082 6146 or VP MedChem Daniel Greve at daniel.greve@orbismedicines.com

You do not need to attach a cover letter to your application, but please include a few sentences in your CV or resume about why you are applying and upload your application using this link. Orbis Medicines is an equal-opportunity employer.

We celebrate diversity and are committed to creating an inclusive environment for all employees.